Cancer Glycolysis I: Entropy Production and Sensitivity Analysis in Stationary State

Using sensitivity analysis and entropy production rate 10 main reactions, among 20 regulating the glycolysis process of AS-30D hepatoma and HeLa tumor cell line in stationary state, were identified. In fact, these 10 fundamental reactions are potential targets in cancer therapy. A high correlation between entropy production rate and intracellular pHi was detected in this work.


Montero S, Martin RR, Guerra A, Casanella O, Cocho G and Nieto-Villar JM

Abstract | Full-Text | PDF

Share this  Facebook  Twitter  LinkedIn  Google+
Flyer image

Abstracted/Indexed in

  • Google Scholar